Korean Clinical Psychology Association
[ Original Article ]
Korean Journal of Clinical Psychology - Vol. 41, No. 1, pp.11-23
ISSN: 1229-0335 (Print) 2733-4538 (Online)
Print publication date 28 Feb 2022
Received 06 Oct 2021 Revised 23 Dec 2021 Accepted 15 Jan 2022
DOI: https://doi.org/10.15842/kjcp.2022.41.1.002

The Relationship Between Prescription Patterns and Symptom-Based Subtypes of Depression Using Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2-RF) Specific Problems Scales in Korean Clinical Sample

Min-Sook Gim1 ; Ji Young Choi2,
1Department of Psychiatry, Sanggye Paik Hospital, Inje University, Seoul, Korea
2Department of Child Studies, Inha University, Incheon, Korea

Correspondence to: Ji Young Choi, Department of Child Studies, University of Inha University, 100 Inha-ro, Michuhol-gu, Incheon, Korea; E-mail: haiminju@inha.ac.kr We have no known conflict of interest to disclose.This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

© 2022 Korean Clinical Psychology Association


We derived five heterogeneous subtypes for 473 Korean depressive disorder patients through a latent profile analysis using the specific problems scale of the Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2-RF), which we used in a previous study (Choi, 2019). In this study, we attempted to confirm the clinical usefulness of specific problem scales by comparing the drug prescription patterns of the five derived subtypes: mild, helpless, somatic, avoidant with anxiety, and irritable with anxiety. Through retrospective medical records of 473 patients with depressive disorder, we investigated their demographic variables, hospitalizations, and prescriptions during the initial, third, and sixth months of treatment. There was a significant difference among the groups in the number of antidepressants prescribed initially and in the third months of treatment. Additionally, we noted differences in antipsychotics prescription in months three and six and sedative/hypnotics prescription in month six. The study results confirmed that the subtypes of depressive disorder based on specific problem scales of the MMPI-2-RF were associated with prescription patterns and clinical course. This finding suggests that subtyping based on multidimensional symptoms, not just the main symptoms of depression, may be useful in establishing a focused treatment plan tailored to the individual characteristics of patients in the initial phase of treatment.


depression, symptom-based subtypes, specific problems scale of MMPI-2-RF, latent profile analysis, prescription patterns

Author contributions statement

M.S. Gim, Associate Professor at Inje University, collected and analyzed the data and prepared the manuscript. J.Y. Choi, Associate Professor at Inha University, supervised the study plan and assisted with the analysis. Both authors participated in the revision of the manuscript and approved the final submission.


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